Depression

More than a low mood. Depression is a common, treatable medical condition that changes how you feel, think, and function, and most people get better with the right care.

Reviewed by Michael Callans, Master’s in Psychology · Last updated June 2026

If you are in crisis. If you are thinking about harming yourself, call or text 988 (Suicide & Crisis Lifeline, US) for free, confidential support, any time. Outside the US, contact your local emergency number.

Key facts

  • Depression (major depressive disorder) is one of the most common mental health conditions worldwide.
  • It is not a sign of weakness, and it is not something you can simply "snap out of."
  • The core treatments are psychotherapy, medication, or both, and they work for most people.
  • Symptoms lasting two weeks or more are a reason to talk to a professional.

What is depression?

Depression is a mood disorder that causes a persistent feeling of sadness, emptiness, or loss of interest, along with physical and cognitive changes that interfere with daily life. Everyone feels down at times, but depression is different: the low mood lasts for weeks or longer and affects work, relationships, sleep, appetite, and the ability to enjoy things you used to.

It is a real medical condition with biological, psychological, and social causes, not a character flaw. The encouraging part is that depression is highly treatable.

Symptoms

Depression looks different from person to person, but common signs include:

A diagnosis of major depression generally involves several of these symptoms present for at least two weeks.

Types of depression

Causes and risk factors

There is no single cause. Depression usually results from a combination of factors:

How depression is treated

Depression is one of the most treatable mental health conditions. Most people respond well to treatment, and a combination often works best.

Psychotherapy

Talk therapy, particularly cognitive behavioral therapy (CBT) and interpersonal therapy, helps you identify and change the thoughts and patterns that fuel depression. For many people it is as effective as medication, and the benefits can last.

Medication

Antidepressants can help correct the brain chemistry involved in depression. They take a few weeks to work and should always be managed by a prescriber. Learn more about antidepressants.

Lifestyle and self-care

Regular physical activity, consistent sleep, social connection, and limiting alcohol all support recovery. These complement, but do not replace, professional treatment for moderate to severe depression.

Ready to talk to someone? A licensed therapist can help you understand what you are experiencing and build a plan that works for you. Find a Therapist

When to seek help

Reach out to a doctor or mental health professional if low mood, loss of interest, or other symptoms last more than two weeks or get in the way of daily life. Seek help immediately if you have thoughts of harming yourself. Depression is treatable, and getting help early makes recovery easier.

Frequently asked questions

Can depression go away on its own?

Mild symptoms sometimes ease with time and self-care, but moderate to severe depression usually needs treatment. Waiting can prolong suffering, so it is worth talking to a professional.

Is depression the same as feeling sad?

No. Sadness is a normal emotion that passes. Depression is a persistent condition that affects mood, body, and thinking for weeks or longer and interferes with daily life.

How long does treatment take?

Many people start to feel better within weeks of beginning therapy or medication, though full recovery varies. Your provider can set expectations based on your situation.

Medical disclaimer. This page is for general education and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified health provider with any questions about a medical condition.